Availability of Clinical Trial Data From Industry‐Sponsored Cardiovascular Trials
نویسندگان
چکیده
منابع مشابه
Availability of Clinical Trial Data From Industry‐Sponsored Cardiovascular Trials
BACKGROUND Industry-sponsored clinical trials produce high-quality data sets that can be used by researchers to generate new knowledge. We assessed the availability of individual participant-level data (IPD) from large cardiovascular trials conducted by major pharmaceutical companies and compiled a list of available trials. METHODS AND RESULTS We identified all randomized cardiovascular inter...
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BACKGROUND Sharing of patient-level clinical trial data has been widely endorsed. Little is known about how extensively these data have been used for cardiometabolic diseases. We sought to evaluate the availability and use of shared data from cardiometabolic clinical trials. METHODS We extracted data from ClinicalStudyDataRequest.com, a large, multisponsor data-sharing platform hosting indivi...
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In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...
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ژورنال
عنوان ژورنال: Journal of the American Heart Association
سال: 2016
ISSN: 2047-9980,2047-9980
DOI: 10.1161/jaha.116.003307